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Best Tulsi for Stress & Mood

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Last reviewed May 2026

Clinical dose: 250โ€“1200 mg

Why Tulsi for Stress & Mood

Tulsi plays a supporting role in stress & mood. Holy basil (Tulsi) is an adaptogenic herb from Ayurvedic medicine. Several RCTs show reductions in stress and anxiety symptoms, though study quality is mixed.

What dose to look for

Clinical studies typically use 250โ€“1200 mg of tulsi. Leaf extract range from RCTs for stress and anxiety. Products below this range may not deliver meaningful results.

What the research says

Tulsi has moderate clinical evidence for stress & mood benefits. Several clinical trials show stress and anxiety reductions, though study quality is mixed Learn more

Clinical research on Holy Basil / Tulsi (Ocimum tenuiflorum)

MODERATE โ€” Emerging RCTs, cortisol confirmed ยท 250โ€“1,200 mg/day

  • โ€ข2022 RCT (100 adults, 250 mg/day, 8 weeks): PSS improved (p=0.003), hair cortisol lower (p=0.025), acute stress buffered (cortisol p=0.001).
  • โ€ขOciBest RCT (150 participants, 1,200 mg/day, 6 weeks): reduced stress symptom scores (pโ‰ค0.05).
  • โ€ข2017 systematic review of 24 studies: all favorable โ€” described as effective adaptogen for modern stresses.
  • โ€ขMechanism: inhibits CRH receptor-1, reduces cortisol/amylase, enhances serotonin/dopamine. Optimal forms: Holixer or OciBest (standardized).
See full Stress & Mood research โ†’
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