About ATP
Oral ATP is rapidly degraded in the gut — supplemented ATP doesn't reliably raise systemic ATP. PEAK ATP (disodium adenosine 5'-triphosphate) is the commercially studied form, with a small number of industry-sponsored RCTs (Wilborn 2013, Jordan 2004) showing modest improvements in strength and body composition at 400 mg/day. Independent replication is sparse. Non-PEAK ATP products that label in activity-unit fluff (e.g. "250 MILLION LCU") use marketing units with no established assay correlation to clinical ATP doses — efficacy at those declarations is unverifiable.
What ATP supports
- May support strength and lean mass at 400 mg/day in resistance-trained users (PEAK ATP trials)
How much ATP to take
The RDA prevents deficiency. The effective range is what clinical trials used to actually move the outcome.
Effective
200–400
mg
PEAK ATP studies (Wilborn 2013, Jordan 2004) used 400 mg/day for 12-15 weeks. Below 200 mg/day shows no measurable effect on performance markers in the available trials.
Clinical evidence
Limited clinical evidence. Small industry-sponsored RCTs (Wilborn 2013, Jordan 2004) at 400 mg/day; oral ATP degrades in the gut so systemic absorption is debated
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