BioStacks

Herb

Arctium lappa

Evidence

Limited
Evidence: 2 of 5 (Limited)

What the evidence says

Burdock root (Arctium lappa) is a traditional medicinal root used in Chinese, Japanese, and European herbal systems for skin conditions, digestion, and 'detoxification.' Rich in inulin-type fructans (~40–50% of dry root weight) plus lignans (arctigenin, arctiin), polyphenolic acids, and polyacetylenes.

One small knee OA RCT (n=36) showed reduced inflammatory markers; otherwise evidence is preclinical or traditional. No meta-analyses or well-powered RCTs exist.

Top Arctium lappa supplements

About Arctium lappa

Burdock root (Arctium lappa) is a traditional medicinal root used in Chinese, Japanese, and European herbal systems for skin conditions, digestion, and 'detoxification.' Rich in inulin-type fructans (~40–50% of dry root weight) plus lignans (arctigenin, arctiin), polyphenolic acids, and polyacetylenes. Human clinical evidence is very limited: one small RCT (Maghsoumi-Norouzabad 2016, n=36 knee OA patients, 6 g/day as tea for 42 days) showed reductions in IL-6, hs-CRP, and malondialdehyde and increased antioxidant capacity. A second RCT examined a burdock-containing complex in asymptomatic H. pylori-positive subjects. No meta-analyses exist. Arctigenin shows anti-inflammatory and anti-cancer activity in preclinical models but has poor oral bioavailability. The inulin fraction provides legitimate prebiotic fiber activity, though not at typical capsule doses. Traditional claims for skin, liver 'detox,' and hair health are not supported by controlled human trials. ⚠️ Members of the Asteraceae family may trigger allergic reactions in people sensitive to ragweed, daisies, chrysanthemums, or marigolds. Possible hypoglycemic interaction — caution with diabetes medications.

What Arctium lappa supports

  • One small RCT (n=36) showed reduced inflammatory markers (IL-6, hs-CRP) in knee osteoarthritis
  • Rich source of inulin-type prebiotic fiber (~40–50% of dried root)
  • Traditional use for skin and liver support — not validated by controlled human trials

How much Arctium lappa to take

The RDA prevents deficiency. The effective range is what clinical trials used to actually move the outcome.

Effective

10003000

mg

Traditional herbal range of 1–3 g/day of dried root or equivalent extract. The only published OA RCT used 6 g/day as tea (three 2 g infusions). No well-powered RCTs have established an optimal clinical dose.

Clinical evidence

Limited clinical evidence. One small knee OA RCT (n=36) showed reduced inflammatory markers; otherwise evidence is preclinical or traditional. No meta-analyses or well-powered RCTs exist.

NIH Fact Sheet