BioStacks

Herb

Cilantro / Coriander Leaf

Evidence

Limited
Evidence: 2 of 5 (Limited)

What the evidence says

Cilantro is the leaf of Coriandrum sativum (the seed is 'coriander'). It is heavily marketed for heavy-metal 'detox'/chelation, almost always paired with chlorella.

Heavy-metal chelation / 'detox' claims are supported only by in-vitro and animal studies plus uncontrolled observations — no randomized controlled trials in humans establish efficacy or dose.

Top Cilantro / Coriander Leaf supplements

About Cilantro / Coriander Leaf

Cilantro is the leaf of Coriandrum sativum (the seed is 'coriander'). It is heavily marketed for heavy-metal 'detox'/chelation, almost always paired with chlorella. Human evidence is essentially absent: the chelation claims rest on in-vitro and rodent data (e.g. lead mobilization in mice) plus a small uncontrolled clinical observation (Omura), none of which establish efficacy or a therapeutic dose in people. As a food, cilantro is a benign source of antioxidants and vitamin K. No established RDA or UL, and no validated chelation dose.

What Cilantro / Coriander Leaf supports

  • Culinary herb promoted for heavy-metal 'detox' — chelation claims are preclinical (in-vitro / animal) only
  • No controlled human trials establish heavy-metal removal or an effective dose

How much Cilantro / Coriander Leaf to take

The RDA prevents deficiency. The effective range is what clinical trials used to actually move the outcome.

Effective

10004000

mg

No therapeutic dose is established for cilantro in heavy-metal 'detox' — there are no human dose-finding trials. The range reflects typical dried-herb amounts (≈1–4 g/day) used in detox products and tinctures, applied only as a dose-adequacy gauge, NOT as evidence of effect. Liquid tinctures usually state a dry-herb equivalent (e.g. '1:3 ratio, equivalent to 500 mg dry cilantro').

Clinical evidence

Limited clinical evidence. Heavy-metal chelation / 'detox' claims are supported only by in-vitro and animal studies plus uncontrolled observations — no randomized controlled trials in humans establish efficacy or dose.

NIH Fact Sheet