About Citrus Bioflavonoids
Citrus bioflavonoids are a group of polyphenolic compounds found in citrus fruits, primarily hesperidin, naringin, rutin, and diosmin. Often included in vitamin C supplements as co-factors. The most clinically studied components are hesperidin (cardiovascular, blood pressure) and diosmin (venous insufficiency — Daflon 500mg is a prescription product in Europe). As a generic 'bioflavonoid complex,' the composition varies widely between products and is rarely standardized, making dosing comparisons difficult. Individual components (hesperidin, rutin) have their own evidence base and are scored separately when listed.
What Citrus Bioflavonoids supports
- May support vascular health and capillary integrity
- Antioxidant and anti-inflammatory properties
How much Citrus Bioflavonoids to take
The RDA prevents deficiency. The effective range is what clinical trials used to actually move the outcome.
Effective
250–1000
mg
Typical supplement range 250–1000 mg/day. Often a mix of hesperidin, naringin, rutin, and other flavanones. Standardized extracts (e.g. Diosmin/Hesperidin 90:10) are better studied.
Clinical evidence
Limited clinical evidence. Mixed flavonoid complex; individual components (hesperidin, diosmin) have moderate evidence, but generic complexes are poorly standardized
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