About Copper
Required for iron transport (via ceruloplasmin), collagen formation, and antioxidant defense through superoxide dismutase (SOD). Copper and zinc compete for absorption—high-dose zinc supplementation (above 50 mg/day) can induce copper deficiency over time. Copper bisglycinate and copper gluconate are well-absorbed supplemental forms. Most multivitamins provide adequate amounts; standalone supplementation is rarely needed unless zinc intake is high.
What Copper supports
- Aids iron metabolism
- Forms connective tissue
- Supports brain development
- Acts as antioxidant
How much Copper to take
Clinical studies typically use 1000–2000 mcg of Copper.
- RDA
- 900 mcg
- Upper limit (UL)
- 10000 mcg
- Effective range
- 1000–2000 mcg
Forms of Copper compared
- Copper bisglycinatePremiumChelated; balanced absorption with minimal GI effects.
- Copper gluconateStandardCommon food-grade form; decent absorption.
- Copper sulfateBudgetPoorly absorbed
- Copper oxideBudgetPoorly absorbed
Clinical evidence
Strong clinical evidence. Essential cofactor for iron transport via ceruloplasmin and collagen formation via lysyl oxidase
NIH Fact Sheet