About Carnosine
L-Carnosine is a dipeptide of beta-alanine and L-histidine, found naturally in high concentrations in muscle and brain tissue. It acts as an intracellular buffer, antioxidant, and anti-glycation agent — preventing the cross-linking of proteins by sugars (AGEs). Levels decline with age, which has made it a popular longevity supplement. Distinct from beta-alanine, which the body uses to synthesize carnosine endogenously. Generally well tolerated. No established RDA/UL.
What Carnosine supports
- Potent anti-glycation agent — helps prevent AGE formation linked to aging
- Concentrated in brain tissue, may support cognitive health
- Acts as an intracellular pH buffer in muscle during exercise
- Antioxidant and metal chelator, supports cellular defense
How much Carnosine to take
Clinical studies typically use 500–1500 mg of Carnosine. Most studies use 500–1000 mg/day for anti-glycation and antioxidant benefits. Higher doses (1500–2000 mg) have been used in cognitive and exercise studies. Often taken in divided doses.
- Effective range
- 500–1500 mg
Clinical evidence
Moderate clinical evidence. Several clinical trials on anti-glycation and antioxidant effects, but most studies are small
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