About Manganese
Cofactor for manganese superoxide dismutase (MnSOD), a critical mitochondrial antioxidant enzyme, and enzymes involved in bone formation and carbohydrate metabolism. Adequate intake is easily met through diet—whole grains, nuts, and tea are rich sources. Supplementation is rarely needed and high doses can be neurotoxic. Often included in multivitamins and bone-support formulas at modest doses.
What Manganese supports
- Supports bone formation
- Aids metabolism
How much Manganese to take
Clinical studies typically use 1.8–5 mg of Manganese.
- RDA
- 2.3 mg
- Upper limit (UL)
- 11 mg
- Effective range
- 1.8–5 mg
Forms of Manganese compared
- Manganese bisglycinatePremiumChelated; well-absorbed and gentle on the stomach.
- Manganese citrateStandardReasonable absorption; common food-grade form.
- Manganese gluconateStandardCommon food-grade form; decent absorption.
- Manganese sulfateBudgetBasic form, lower absorption
Clinical evidence
Strong clinical evidence. Cofactor for mitochondrial antioxidant enzyme MnSOD; easily met through diet, supplementation rarely needed
NIH Fact Sheet