About Oleuropein
The primary bioactive polyphenol in olive leaves. RCTs using olive leaf extract standardized to oleuropein show modest blood pressure reduction in pre-hypertensive subjects and improved endothelial function. Anti-inflammatory and antimicrobial properties demonstrated in vitro. Verbascoside (acteoside) is a related phenylpropanoid often co-extracted with oleuropein from olive fruit/leaf — similar antioxidant profile. Bioavailability is moderate; extensively metabolized after absorption.
What Oleuropein supports
- Olive leaf RCTs show modest blood pressure reduction
- Anti-inflammatory and antioxidant properties
How much Oleuropein to take
The RDA prevents deficiency. The effective range is what clinical trials used to actually move the outcome.
Effective
5–50
mg
Olive leaf extract RCTs typically deliver 15–50 mg/day oleuropein from 500–1000 mg extract. Lower doses (4–10 mg) found as sub-components of olive fruit extracts.
Clinical evidence
Limited clinical evidence. Blood pressure RCTs use olive leaf extract standardized to oleuropein; isolated oleuropein data is limited — most evidence is from whole extract studies
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