About PABA
A compound structurally part of the folic acid molecule, historically grouped with B-vitamins (sometimes called Vitamin Bx). Found in some B-complex formulas as a legacy ingredient. Claims for anti-graying and skin health trace back to a single 1941 study that was never replicated. No meaningful RCTs support oral supplementation for any health outcome. Can cause liver toxicity at high doses (>8g/day). Not an essential nutrient — no RDA established.
What PABA supports
- Legacy B-complex ingredient with no established clinical benefit
How much PABA to take
The RDA prevents deficiency. The effective range is what clinical trials used to actually move the outcome.
Effective
30–400
mg
Common supplement doses range from 30-400 mg/day. Higher doses (>8g) are associated with liver toxicity. No established therapeutic range from RCTs.
Clinical evidence
Limited clinical evidence. No RCTs support oral PABA for any health outcome; anti-graying claims are based on unreplicated 1940s research
Examine.com