About Rutin
Rutin is a flavonoid glycoside (quercetin bound to rutinose) found in buckwheat, citrus, and asparagus. Best studied for chronic venous insufficiency — a Cochrane review found moderate evidence that oxerutins (including rutin derivatives) reduce edema and symptoms in CVI. Also demonstrates antioxidant and anti-inflammatory properties in preclinical models. Less bioavailable than free quercetin but more stable. Enzymatic conversion to quercetin occurs in the gut.
What Rutin supports
- Supports vascular health and capillary integrity
- Antioxidant and anti-inflammatory flavonoid
- May reduce leg swelling in venous insufficiency
How much Rutin to take
The RDA prevents deficiency. The effective range is what clinical trials used to actually move the outcome.
Effective
250–500
mg
Clinical studies use 250–500 mg/day. Some venous insufficiency trials use up to 1000 mg/day as oxerutins.
Clinical evidence
Moderate clinical evidence. Cochrane review found moderate evidence for reducing swelling in chronic venous insufficiency
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