About Vitamin C
Potent antioxidant and cofactor for collagen synthesis, immune function, and iron absorption. Liposomal vitamin C provides significantly higher bioavailability than standard ascorbic acid by encapsulating the molecule in phospholipid spheres for enhanced cellular uptake. Buffered forms (mineral ascorbates like calcium or magnesium ascorbate) reduce gastric irritation for sensitive stomachs. Smokers need an additional 35 mg/day.
What Vitamin C supports
- Strengthens immune defense
- Builds collagen for skin
- Enhances iron absorption
- Speeds wound healing
How much Vitamin C to take
Clinical studies typically use 250–2000 mg of Vitamin C. Common supplement range; UL is 2000 mg/day.
- RDA
- 90 mg
- Upper limit (UL)
- 2000 mg
- Effective range
- 250–2000 mg
Forms of Vitamin C compared
- Calcium ascorbatePremiumBuffered, gentle on the stomach.
- Liposomal vitamin CPremiumPhospholipid carriers boost absorption and serum levels.
- Sodium ascorbateStandardBuffered for sensitive stomachs; watch sodium load at high doses.
- Ester-CBudgetMarketing claims, unclear benefit over standard forms
- Ascorbyl palmitateBudgetFat-soluble form, limited bioavailability data
- Ascorbic acidBudgetStandard form — absorption drops above 1,000mg
Clinical evidence
Strong clinical evidence. Cochrane review of 29 trials found it reduces cold duration 8% in adults; key cofactor for collagen synthesis
NIH Fact Sheet