This bone-support combo delivers 1,000mg of **Calcium**, 400mg of **Magnesium**, and 15mg of **Zinc** alongside 400 IU of **Vitamin D3** — a formula that looks solid on the label but has a significant absorption gap. All three minerals use oxide or carbonate forms, which are the least bioavailable options. **Magnesium Oxide** absorbs at roughly 4%, meaning your body may only use a fraction of that 400mg. **Calcium Carbonate** requires stomach acid to break down, so you'll need to take it with meals.

**Vitamin D3** at 400 IU falls short of the 1,000–5,000 IU range supported by clinical consensus for maintaining healthy blood levels. Since vitamin D is essential for calcium absorption — without enough, your body absorbs only 10–15% of the calcium — this underdose limits the formula's primary purpose. The magnesium-D3 synergy is a plus in theory, since magnesium activates vitamin D, but both are held back by low dosing or poor form.

The 3-tablet serving size also means you're getting 1,000mg of calcium at once, well above the 500mg threshold where absorption drops off sharply. Splitting your dose across meals would help, but the label directs you to take all three tablets together.

BioStacks
21st Century

Calcium Magnesium Zinc + D3

3 Tablets · 30 servings · $0.18/serving

iHerbAmazon

Best for

DentalBone & JointImmune

Ingredients (4)

Vitamin D3

40%

Dose

400 IU

Target

1000–5000 IU

Form

Premium

Calcium

100%

Dose

1000 mg

Target

200–600 mg

Form

Budget

Zinc

100%

Dose

15 mg

Target

15–30 mg

Form

Budget

Magnesium

100%

Dose

400 mg

Target

100–400 mg

Form

Budget

Other Ingredients (3)

MaltodextrinBinder

Spikes blood sugar faster than table sugar (glycemic index 85–105). Research links it to gut bacteria changes that may promote intestinal inflammation (Nickerson et al. 2015). Used as a cheap filler — adds nothing beneficial.

Microcrystalline CelluloseBinder

Plant-derived cellulose used as a binder and filler in supplements

Croscarmellose SodiumDisintegrant

Cross-linked cellulose derivative used as a superdisintegrant

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

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