If you're looking for mood support, **St. John's Wort** is one of the most studied herbal options available — multiple meta-analyses show it can help with mild-to-moderate low mood, with effect sizes comparable to standard treatments in some trials. This product delivers 300mg standardized to 0.3% hypericin, which matches the exact dose and standardization used in the majority of clinical research.

The one-capsule-per-day dosing makes it straightforward. Some studies used 300mg three times daily (900mg total), so depending on your needs, you may want to discuss higher intake with a healthcare professional.

St. John's Wort has significant drug interactions — it can reduce the effectiveness of birth control, blood thinners, antidepressants (SSRIs/MAOIs), and other medications by accelerating their metabolism. This is clearly flagged in the product's own warnings, and you should take it seriously before starting.

BioStacks
California Gold Nutrition EuroHerbs

St. John's Wort 300 mg

Capsule · 60 servings · $0.11/serving

14 / 100Very Poor

Score Breakdown

Formulation
18
Safety
80
Final score
14/100

Ingredients (1)

St. John's Wort Flowering Tops Extract300 mg

50% of effective dose

Label Nutrition Facts

Other Ingredients

Fillers, coatings, and additives

3Safe2Caution

MaltodextrinBinder

Caution

Rice FlourFiller

Caution

Silicon DioxideAnti-caking

Safe

Microcrystalline CelluloseBinder

Safe

Stearic AcidLubricant

Safe

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.