A classic joint support combination, but the per-serving doses land below the clinical thresholds for its two headlining ingredients. You're getting 750mg of **Glucosamine** (as GreenGrown HCl) and 600mg of **Chondroitin Sulfate** — the GAIT trial that established this pairing used 1,500mg and 1,200mg respectively, so you're at half the studied doses in each serving.
**OptiMSM** at 500mg is the distillation-purified form with the strongest research behind it, but joint studies typically used 1,000-3,000mg daily. **Hyaluronic Acid** at 50mg just reaches the bottom of the studied range, though skin hydration research typically used 120mg or more. The shellfish-free glucosamine (corn-derived) is a plus if you have allergies.
The main gap here is dose across the board. If you follow the label's 2-capsule serving, every core ingredient except hyaluronic acid falls meaningfully short of clinical doses. You'd need to double your daily intake to approach the ranges used in research — which cuts your 60-day supply in half.
BioStacks
California Gold Nutrition
Glucosamine, Chondroitin, MSM plus Hyaluronic Acid
2 Capsules · 60 servings · $0.30/serving
Best for
Ingredients (4)
Hyaluronic Acid
100%Dose
50 mg
Target
50–200 mg
Form
Standard
GreenGrown
75%Dose
750 mg
Target
1000–1500 mg
Form
Premium
Chondroitin Sulfate
75%Dose
600 mg
Target
800–1200 mg
Form
Standard
OptiMSM Methyl-Sulfonyl-Methane
50%Dose
500 mg
Target
1000–3000 mg
Form
—
Other Ingredients (2)
Magnesium StearateLubricant
A salt of stearic acid used as a lubricant in tablet and capsule production
Microcrystalline CelluloseBinder
Plant-derived cellulose used as a binder and filler in supplements
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.