If you need comprehensive energy and metabolic support, this B complex hits the clinical range across the board. **Thiamine** at 60mg, **Riboflavin** at 75mg, **Vitamin B6** at 50mg, and **Pantothenic Acid** at 100mg all land squarely within studied supplemental doses. **Vitamin B12** at 1,000mcg as methylcobalamin gives you the body-ready form at a well-researched dose.

**Folate** is delivered as Quatrefolic (methylfolate) at 400mcg DFE — the active form your body can use directly, which matters especially if you carry an MTHFR gene variant that impairs folic acid conversion. B6 also uses a blend that includes P5P, the active form. These form choices mean your body spends less energy converting inactive vitamins.

The only real gap is **Biotin** at 600mcg, which falls below the 1,000mcg minimum in supplement research — though biotin deficiency is rare and this dose still covers the RDA 20 times over. What this means for you: for most people, that's a non-issue.

BioStacks
Doctor's Best

Fully Active B Complex with Quatrefolic

1 Capsule · 60 servings · $0.30/serving

iHerbAmazon

Best for

EnergyGeneral Health

Ingredients (9)

Vitamin B12

100%

Dose

1000 mcg

Target

250–5000 mcg

Form

Premium

Pantothenic Acid

100%

Dose

100 mg

Target

50–500 mg

Form

Premium

Folate

100%

Dose

400 mcg DFE

Target

400–800 mcg

Form

Premium

Thiamine

100%

Dose

60 mg

Target

25–100 mg

Form

Premium

Vitamin B6

100%

Dose

50 mg

Target

25–100 mg

Form

Premium

Other Ingredients (4)

Magnesium StearateLubricant

A salt of stearic acid used as a lubricant in tablet and capsule production

Silicon DioxideAnti-caking

Fine silica powder used to prevent clumping

HypromelloseCapsule

Plant-derived capsule material from cellulose

Microcrystalline CelluloseBinder

Plant-derived cellulose used as a binder and filler in supplements

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

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