This product targets metabolic and gut health, but its headline ingredient falls short on dosing. **Berberine Hydrochloride** at 400mg is the strongest ingredient here — it has robust clinical evidence for supporting blood sugar and insulin sensitivity, but studies typically use 500–1,500mg daily. You're getting 80% of the minimum studied dose, so you'd need to add another capsule beyond the label's recommendation to reach the clinical floor.
**L-Arabinose** (branded as Sukre) is dosed at 500mg, but the research on blunting post-meal blood sugar spikes used 2,000–7,500mg per dose — putting this at roughly 25% of the minimum effective amount. **Akkermansia muciniphila** provides just 10mg against a studied range of 25–100mg, and **Triacetin** (branded as TriBiome) has no human clinical trials establishing an effective dose at all.
The core issue is that three of the four ingredients are dosed well below their studied ranges, and one lacks human evidence entirely. Berberine carries this formula, but even it needs a higher daily intake to match what the research supports.
Best for
Ingredients (4)
Berberine Hydrochloride
80%Dose
400 mg
Target
500–1500 mg
Form
Premium
TriBiome (Triacetin)
40%Dose
200 mg
Target
500–3000 mg
Form
—
Akkermansia muciniphila
40%Dose
10 mg
Target
25–100 mg
Form
—
Sukre (L-arabinose)
25%Dose
500 mg
Target
2000–7500 mg
Form
—
Other Ingredients (5)
Magnesium StearateLubricant
A salt of stearic acid used as a lubricant in tablet and capsule production
Silicon DioxideAnti-caking
Fine silica powder used to prevent clumping
Microcrystalline CelluloseBinder
Plant-derived cellulose used as a binder and filler in supplements
Microcrystalline CelluloseBinder
Plant-derived cellulose used as a binder and filler in supplements
Sunflower LecithinEmulsifier
Non-GMO, non-allergenic emulsifier derived from sunflower seeds
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.