KAL Betaine HCl+ targets stomach-acid and protein-digestion support, but at 328mg of **Betaine HCl** per tablet it lands below the doses digestive protocols typically use. The idea is to add hydrochloric acid to your stomach to help break down protein when your own acid is suspected to be low. Your label shows this as 250mg of betaine from 328mg of betaine hydrochloride, while the typical digestive range runs 650–2,500mg and the one study that actually measured its effect on stomach acid used 1,500mg — so a single tablet gives you roughly half the usual starting amount. Evidence is limited overall: no controlled trials have shown betaine HCl improves digestion or nutrient absorption.

The 130mg of **Pepsin** pairs with the acid as a protein-digesting enzyme and sits inside the typical 50–300mg formulation range. The catch is that pepsin's strength is properly measured in activity units, not milligrams, so the 130mg figure alone doesn't tell you how active it is — and no controlled human trials back supplemental pepsin for digestive outcomes. The 32mg of calcium comes from calcium carbonate in the tablet base, far below a dose that contributes to any health goal.

The label suggests one tablet with a meal, so reaching the 650mg+ that digestive protocols start from would mean two or more per meal. Worth knowing: betaine HCl can trigger heartburn or stomach irritation, especially if your stomach acid isn't genuinely low — this is a targeted tool for suspected low stomach acid, not a general digestive aid.

BioStacks
KAL

Betaine HCl+

1 Tablet · 100 servings · $0.12/serving

iHerbAmazon
35 / 100Poor

Score Breakdown

Formulation
35
Safety
100
Final score
35/100

Ingredients (3)

Pepsin

100%

Dose

130 mg

Target

50–300 mg

Form

—

Betaine HCl

50%

Dose

328 mg

Target

650–2500 mg

Form

Premium

Calcium

32 mg

Trace amount — not scored

Other Ingredients (3)

Silicon DioxideAnti-caking

Fine silica powder used to prevent clumping

Magnesium StearateLubricant

A salt of stearic acid used as a lubricant in tablet and capsule production

Microcrystalline CelluloseBinder

Plant-derived cellulose used as a binder and filler in supplements

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

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