You're getting 500mg of **Relora** — a patented magnolia and phellodendron bark blend — right at the standard dose used in the two clinical trials that showed reduced self-reported stress and anxiety. At one capsule daily, you're hitting the clinical range without needing to split doses throughout the day, which is convenient for a stress-support product.

The formula also includes 100mg of **Oligonol**, a lychee-derived polyphenol extract. This sits at the minimum dose from a single small study on exercise-induced cortisol, but there are no human trials testing it for everyday psychological stress. Its role here is more speculative than proven.

The honest caveat: both ingredients carry limited clinical evidence. **Relora** has only two small, manufacturer-funded trials, and **Oligonol** has just one. The stress-reduction results are based on self-reported questionnaires rather than objective cortisol measurements, so the "cortisol balance" in the name oversells what the research actually showed.

BioStacks
Life Extension

Cortisol-Stress Balance

1 Capsule · 30 servings · $1.15/serving

42 / 100Average

Score Breakdown

Formulation
42
Safety
100
Final score
42/100

Ingredients (2)

Relora500 mg

Within effective range

Oligonol100 mg

Within effective range

Other Ingredients

Fillers, coatings, and additives

3Safe

Silicon DioxideAnti-caking

Safe

StarchBinder

Safe

Microcrystalline CelluloseBinder

Safe

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.