**Magtein Magnesium L-Threonate** at 2,000mg per serving (144mg elemental magnesium) — this is the exact dose used in the MIT-developed human trials studying memory and cognitive function. L-threonate is the only magnesium form shown to meaningfully raise brain magnesium levels, making this a targeted pick if your goal is cognitive support rather than general magnesium supplementation.

Your 144mg of elemental magnesium falls comfortably within the 100–400mg clinical supplemental range, and the premium form means absorption isn't a concern. The brain-specific research also gives this product relevance for sleep and stress — magnesium broadly supports nervous system relaxation, and the threonate form may offer additional benefit for mood and mental clarity.

The tradeoff is that 144mg is modest if you're looking for whole-body magnesium coverage — muscle recovery, heart rhythm, or bone support typically call for 300–400mg daily. If brain health is your priority, this delivers. If you need broader magnesium support, you'd want to supplement with an additional form.

BioStacks
Life Extension

Life Extension, Neuro-Mag, Magnesium L-Threonate, 90 Vegetarian Capsules (48 mg per Capsule)

3 Capsules · 30 servings · $1.05/serving

iHerbAmazon

Best for

Sleep

Ingredients (1)

Magnesium

100%

Dose

144 mg

Target

100–400 mg

Form

Premium

Other Ingredients (5)

Silicon DioxideAnti-caking

Fine silica powder used to prevent clumping

Vegetable StearateLubricant

A plant-derived salt of stearic acid (typically magnesium or calcium) used as a tablet lubricant

Microcrystalline CelluloseBinder

Plant-derived cellulose used as a binder and filler in supplements

Stearic AcidLubricant

Saturated fatty acid used as tablet lubricant

Microcrystalline CelluloseBinder

Plant-derived cellulose used as a binder and filler in supplements

How to Take It

Best taken in the evening

Magnesium L-threonate is designed to raise magnesium in the brain — shown in animals. The human cognition trial dosed 1.5–2 g/day, usually split with a dose in the evening.

With or without food
Space it a couple of hours from Iron and Calcium

General guidance based on the ingredients, not a substitute for the label or your doctor.

Price Check

$31.50

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Pricier than 79% of 579 magnesium supplements

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from the NIH Office of Dietary Supplements and the National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. studied ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

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