Life Extension uses **NIAGEN**, the patented nicotinamide riboside form behind virtually every published human trial on NR. That's the gold standard for raising NAD+ levels — the coenzyme your cells rely on for energy production, DNA repair, and activating the sirtuin pathways linked to healthy aging. The form quality here is as good as it gets.
The issue is dose. At 100 mg per capsule with a one-capsule daily serving, you're getting well below the 250–1,000 mg range used in clinical research. Human studies show NR raises blood NAD+ levels in a dose-dependent manner, but the meaningful increases (50%+ above baseline) come at 300 mg and above. At 100 mg, you're at 40% of the minimum studied dose.
If you want to reach a clinically relevant intake, you'd need to take 3 capsules daily — which burns through the 30-capsule bottle in 10 days. Life Extension also makes a 300 mg version of this product, which gets you into the studied range in a single capsule.
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What it does
The product name and ingredient list do not agree; purpose cannot be confirmed.
NAD+ Precursor (NR)
niagenPremium
Label lists NIAGEN Nicotinamide Riboside (100 mg). Benefit information is limited.
Ingredients (1)
Other ingredients
Silicon DioxideAnti-caking
Fine silica powder used to prevent clumping
Vegetable StearateLubricant
A plant-derived salt of stearic acid (typically magnesium or calcium) used as a tablet lubricant
Microcrystalline CelluloseBinder
Plant-derived cellulose used as a binder and filler in supplements
Microcrystalline CelluloseBinder
Plant-derived cellulose used as a binder and filler in supplements
Lab testing
How to take it
With or without food
On the label
Read the entire label and follow the directions carefully prior to use. Directions: Take one (1) capsule daily, or as recommended by a healthcare practitioner.
Price check
$18.00
Cheaper than 99% of 17 NAD+ precursor (NR) supplements
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from the NIH Office of Dietary Supplements and the National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. studied ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.
Not medical advice. Consult your healthcare professional.