Designed to support your mood and sleep through serotonin production, this formula delivers 1,000mg of **L-Tryptophan** per three-capsule serving — right at the top of the clinical range used in research on sleep onset and emotional well-being. That's a full therapeutic dose, and the inclusion of 66mg **Niacin** (as niacinamide) helps ensure your body channels tryptophan toward serotonin rather than diverting it to make niacin on its own.
You're also getting 250mg of **L-Lysine** and a 285mg proprietary blend of hops and rosemary extracts. Lysine may help modulate serotonin receptors involved in stress-related anxiety, though 250mg is well below the 1,000mg+ doses studied for that purpose. The hops extract (Perluxan) has some preliminary evidence for calming support.
The main caveat is the three-capsule serving size — you need all three to reach the studied tryptophan dose. If you take fewer, you're getting a proportionally reduced benefit. Also worth noting: the precautions flag interactions with SSRIs and MAOIs, so check with your doctor if you're on mood-related medication.
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What it does
A combination of 3 label ingredients.
Tryptophan
Mixed formsGrade —
Label lists L-Tryptophan (1000 mg). Benefit information is limited.
Vitamin B3
niacinamideStandard
Helps convert food into cellular energy and supports normal metabolic reactions.
Ingredients (4)
Other ingredients
MaltodextrinBinder
Spikes blood sugar faster than table sugar (glycemic index 85–105). Research links it to gut bacteria changes that may promote intestinal inflammation (Nickerson et al. 2015). Used as a cheap filler — adds nothing beneficial.
Silicon DioxideAnti-caking
Fine silica powder used to prevent clumping
Vegetable StearateLubricant
A plant-derived salt of stearic acid (typically magnesium or calcium) used as a tablet lubricant
Microcrystalline CelluloseBinder
Plant-derived cellulose used as a binder and filler in supplements
Microcrystalline CelluloseBinder
Plant-derived cellulose used as a binder and filler in supplements
StarchBinder
Carbohydrate polymer used as a binder, filler, and disintegrant in tablets and capsules
Microcrystalline CelluloseBinder
Plant-derived cellulose used as a binder and filler in supplements
Lab testing
How to take it
On an empty stomach
Keep it away from protein-heavy meals
Space it a couple of hours from SAMe
On the label
Read the entire label and follow the directions carefully.
Do not combine with St. John's Wort
Each of these raises serotonin activity on top of St. John's Wort, and together they can trigger serotonin syndrome — agitation, rapid heartbeat, raised blood pressure. Not without medical supervision.
Price check
$24.00
$0.80 / serving
Near the median of 18 tryptophan supplements
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from the NIH Office of Dietary Supplements and the National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. studied ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.
Not medical advice. Consult your healthcare professional.