**Berberine** at 500mg per capsule, with a label recommendation of two daily — putting you at 1,000mg, right in the middle of the 500–1,500mg range used in clinical studies for blood sugar and lipid support. At that dose, you're getting strong metabolic coverage — multiple meta-analyses show meaningful effects on fasting glucose, insulin sensitivity, and triglyceride levels.

The form here is berberine hydrochloride, which is the standard form used in most clinical research. It has relatively low oral bioavailability (~5%), so taking it with meals as directed helps both absorption and reduces the GI discomfort that berberine is known for at higher doses.

If you only take one capsule daily, you're at the very bottom of the studied range — enough for mild support, but the two-capsule dose is where the stronger clinical results come from. Worth noting: berberine can interact with several medications, so check with your doctor if you're on anything for blood sugar or cholesterol.