Take all three daily softgels as directed and you're getting 1,200mg of **Berberine HCl** — solidly within the 500–1,500mg range used across multiple meta-analyses for supporting healthy blood sugar, insulin sensitivity, and cholesterol levels. The divided dosing (one softgel three times daily with meals) is exactly how clinical trials administered berberine, which matters because it has a short half-life and needs consistent blood levels throughout the day to work.

The softgel format uses **MCT Oil** as a fat-based carrier, which may help with absorption since standard berberine HCl is notoriously hard for your body to absorb — only about 5% reaches your bloodstream. The MCT itself is dosed far below its own clinical range, so it's functioning purely as a delivery vehicle here, not as a standalone active.

If you experience the GI discomfort berberine is known for at this dose, more bioavailable forms like dihydroberberine can deliver similar effects at much lower doses — worth knowing before you write off the ingredient entirely.

BioStacks
NOW

Berberine Glucose Support

Capsule · 1 Softgel × 3/day · 90 servings

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What it does

A combination of 2 label ingredients.

Berberine HCl

Form not confirmedGrade —

Label lists Berberine Hydrochloride (400 mg). Benefit information is limited.

MCT oil

Form not confirmedGrade —

Provides dietary fat and raises ketones; consistent endurance-performance benefits have not been demonstrated.

Metabolism
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Ingredients (2)

Nutrition

Calories, macros & sodium.

  • Calories5 Calorie(s)
  • Total Fat0.5 Gram(s)
    • Saturated Fat0.5 Gram(s)

Other ingredients

Caramel ColorColor

Class III and IV caramel colors contain 4-methylimidazole (4-MEI), classified by IARC as Group 2B (possibly carcinogenic to humans) in 2011 (Monograph Vol. 101). California Prop 65 lists 4-MEI as a known carcinogen; products delivering >29 mcg/day require a cancer warning label. NTP TR-535 (2007) found 4-MEI caused lung tumors in mice. Major cola brands (Coca-Cola, Pepsi) voluntarily reformulated 2012-2014 to reduce 4-MEI below California thresholds. Because labels never specify Class I (sugar + heat only, safer) vs Class III/IV (ammonia-process, contains 4-MEI), consumers cannot verify which they're consuming. Combined with the additive's purely cosmetic purpose, the risk:benefit ratio is unfavorable for any supplement.

BeeswaxCoating

Natural wax produced by honeybees, used as a coating and binding agent in softgels and tablets

GelatinCapsule

Protein derived from collagen, used in traditional capsule shells

GlycerinHumectant

Sweet-tasting liquid used in soft capsules and liquids

Sunflower LecithinEmulsifier

Non-GMO, non-allergenic emulsifier derived from sunflower seeds

Purified WaterSolvent

Water meeting USP specifications used as solvent/vehicle in gummies and liquids

Lab testing

How to take it

With food
Split into 3 doses across the day

On the label

Suggested Usage: Take 1 softgel 3 times daily with food.

Price check

$24.49

$20$50

Cheaper than 67% of 81 berberine HCl supplements

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from the NIH Office of Dietary Supplements and the National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. studied ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

Not medical advice. Consult your healthcare professional.

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