Take all three daily softgels as directed and you're getting 1,200mg of **Berberine HCl** — solidly within the 500–1,500mg range used across multiple meta-analyses for supporting healthy blood sugar, insulin sensitivity, and cholesterol levels. The divided dosing (one softgel three times daily with meals) is exactly how clinical trials administered berberine, which matters because it has a short half-life and needs consistent blood levels throughout the day to work.
The softgel format uses **MCT Oil** as a fat-based carrier, which may help with absorption since standard berberine HCl is notoriously hard for your body to absorb — only about 5% reaches your bloodstream. The MCT itself is dosed far below its own clinical range, so it's functioning purely as a delivery vehicle here, not as a standalone active.
If you experience the GI discomfort berberine is known for at this dose, more bioavailable forms like dihydroberberine can deliver similar effects at much lower doses — worth knowing before you write off the ingredient entirely.
BioStacks
Best for
Ingredients (2)
Berberine Hydrochloride
100%Dose/day
1200 mg
Target
500–1500 mg
Form
Premium
MCT Oil
14%Dose/day
714 mg
Target
5000–15000 mg
Form
—
Nutrition
Calories, macros & sodium.
- Calories5 Calorie(s)
- Total Fat0.5 Gram(s)
- Saturated Fat0.5 Gram(s)
Other Ingredients (6)
Caramel ColorColor
Class III and IV caramel colors contain 4-methylimidazole (4-MEI), classified by IARC as Group 2B (possibly carcinogenic to humans) in 2011 (Monograph Vol. 101). California Prop 65 lists 4-MEI as a known carcinogen; products delivering >29 mcg/day require a cancer warning label. NTP TR-535 (2007) found 4-MEI caused lung tumors in mice. Major cola brands (Coca-Cola, Pepsi) voluntarily reformulated 2012-2014 to reduce 4-MEI below California thresholds. Because labels never specify Class I (sugar + heat only, safer) vs Class III/IV (ammonia-process, contains 4-MEI), consumers cannot verify which they're consuming. Combined with the additive's purely cosmetic purpose, the risk:benefit ratio is unfavorable for any supplement.
BeeswaxCoating
Natural wax produced by honeybees, used as a coating and binding agent in softgels and tablets
GelatinCapsule
Protein derived from collagen, used in traditional capsule shells
GlycerinHumectant
Sweet-tasting liquid used in soft capsules and liquids
Sunflower LecithinEmulsifier
Non-GMO, non-allergenic emulsifier derived from sunflower seeds
Purified WaterSolvent
Water meeting USP specifications used as solvent/vehicle in gummies and liquids
Track this supplement in your stack
Get personalized insights, interactions, and coverage recommendations.
Get Started FreeSimilar Supplements
Products that cover similar health dimensions based on their ingredients.
Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.