This product delivers 100 mg of **5-HTP** (5-Hydroxytryptophan) per chewable tablet, sourced from Griffonia simplicifolia seeds. 5-HTP is a direct precursor to serotonin, the neurotransmitter that regulates mood and converts into melatonin to support your sleep-wake cycle. At 100 mg, this sits at the entry point of the commonly studied range (100-300 mg), making it a reasonable starting dose.

The clinical evidence behind 5-HTP for stress and mood is limited. A few small trials suggest it may support serotonin levels, but there are no large-scale meta-analyses confirming its effectiveness for stress relief in otherwise healthy individuals. The mechanistic logic is strong — your body does use 5-HTP to make serotonin — but the human trial data has not caught up yet. If you respond well to the 100 mg dose, the research supports going up to 300 mg.

One important safety note: 5-HTP should not be combined with SSRIs, MAOIs, or triptan medications, as stacking serotonin-boosting compounds raises the risk of serotonin syndrome, a potentially serious condition. The chewable format and citrus flavoring make this easy to take — best on an empty stomach at bedtime as directed.

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BioStacks

NOW

Chewable 5-HTP 100 mg Natural Citrus Flavor

Tablet · 90 servings · $0.19/serving

36 / 100Poor

Supports

Score Breakdown

Formulation
41
Safety
87
Final score
36/100

Ingredients (1)

5-Hydroxytryptophan100 mg

Within effective range

Label Nutrition Facts

Active Ingredients

From the label · % Daily Value

DV%

5-Hydroxytryptophan100 mg

Other Ingredients

Fillers, coatings, and additives

6Safe1Caution

XylitolSweetener

Caution

Silicon DioxideAnti-caking

Safe

Citric AcidAcidulant

Safe

Microcrystalline CelluloseBinder

Safe

Microcrystalline CelluloseBinder

Safe

Natural FlavorsFlavor

Safe

Stearic AcidLubricant

Safe

Annatto seed extract (annatto)

Unknown

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.