Each capsule delivers 300mg of **Milk Thistle Extract** standardized to 80% silymarin — giving you 240mg of the active flavonoids responsible for liver-protective effects. That puts a single capsule right in the middle of the 150–600mg clinical range. The label suggests 1–3 capsules daily, so at the full 3-capsule dose you're getting 900mg, well above what most studies used.

**Dandelion** (100mg) and **Artichoke** (50mg) round out the formula as traditional liver-support herbs. Both are dosed well below their studied ranges (500–1,500mg for dandelion, 300–640mg for artichoke), so they're contributing minimally at these amounts. Artichoke has moderate clinical evidence for bile flow and digestion, but you'd need several times this dose to match the research.

The milk thistle itself uses a standard extract rather than a phytosome form, which means lower absorption of the key compound silybin. If your main goal is liver support, the silymarin dose is solid — but getting more silybin into your bloodstream would require a phytosome-bound form.

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NOW

Double Strength Milk Thistle Extract 300 mg

1 Capsule · 200 servings · $0.13/serving

iHerbAmazon

Best for

Liver

Ingredients (3)

Milk Thistle Fruit, Seed Extract

100%

Dose

240 mg

Target

150–600 mg

Form

Not listed

Artichoke

17%

Dose

50 mg

Target

300–640 mg

Form

—

Dandelion

20%

Dose

100 mg

Target

500–1500 mg

Form

—

Other Ingredients (4)

Magnesium StearateLubricant

A salt of stearic acid used as a lubricant in tablet and capsule production

Silicon DioxideAnti-caking

Fine silica powder used to prevent clumping

HypromelloseCapsule

Plant-derived capsule material from cellulose

Microcrystalline CelluloseBinder

Plant-derived cellulose used as a binder and filler in supplements

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

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