At 1,000 mcg per lozenge, **Methylcobalamin** lands right in the middle of the clinically studied range (250–5,000 mcg) for supporting energy, nerve function, and red blood cell production. The directions suggest 1–2 lozenges daily, giving you up to 2,000 mcg if you take two — plenty to maintain healthy B12 levels for most people.

The lozenge format is a practical choice here. You dissolve it in your mouth, which allows B12 to absorb through the oral mucosa — bypassing the gut, where absorption depends on intrinsic factor that naturally declines with age. This makes it especially relevant if you're over 50 or have digestive concerns. The form itself is the bioactive version your body can use directly, with no conversion step required.

If you're vegan or correcting a known deficiency, you may want to start at 2 lozenges daily. For maintenance, one lozenge provides a solid dose — though it sits at the lower end of what's typically supplemented.

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NOW

Methyl B-12 1,000 mcg

1 Lozenge · 100 servings · $0.08/serving

iHerbAmazon

Best for

Energy

Ingredients (1)

Vitamin B12

100%

Dose

1000 mcg

Target

250–5000 mcg

Form

Premium

Other Ingredients (8)

FructoseSweetener

Added free fructose is metabolized in the liver and at habitual intake is linked to elevated triglycerides, hepatic fat accumulation, and insulin resistance; an avoidable sugar load with no supplement benefit.

SorbitolSweetener

A FODMAP sugar alcohol that may trigger GI discomfort (bloating, gas) in individuals with IBS or sorbitol malabsorption, even at small amounts found in supplements. Avoided in low-FODMAP diets.

Magnesium StearateLubricant

A salt of stearic acid used as a lubricant in tablet and capsule production

Natural FlavorsFlavor

Broad regulatory category of flavor constituents derived from natural sources. Composition is proprietary and not disclosed — 'Natural Flavors' can include several hundred different compounds depending on the target flavor profile, including hexane-extracted constituents and proprietary carrier solvents. 'Natural' is a regulatory definition (21 CFR §101.22), not a safety guarantee.

Citric AcidAcidulant

Natural acid derived from citrus fruits

Hydroxypropyl CelluloseBinder

An inert modified-cellulose polymer used as a binder, film-former, and disintegrant.

Microcrystalline CelluloseBinder

Plant-derived cellulose used as a binder and filler in supplements

Stearic AcidLubricant

Saturated fatty acid used as tablet lubricant

How to Take It

Best taken in the morning

Many people prefer it earlier in the day; there's no evidence timing changes anything. Absorption is fine with or without food.

With or without food

On the label

Suggested usage: Take 1 lozenge 1 to 2 times daily. Chew lozenge or hold in mouth until dissolved and swallow.

General guidance based on the ingredients, not a substitute for the label or your doctor.

Price Check

$7.95

$10$20

Cheaper than 93% of 235 vitamin B12 supplements

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from the NIH Office of Dietary Supplements and the National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. studied ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

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