If you're looking for methylation and performance support, this product hits the clinical sweet spot. A single three-tablet serving delivers 3,000mg of **Trimethylglycine (TMG)**, landing squarely in the 2,500–6,000mg range studied in research on homocysteine reduction and exercise performance.
At 3,000mg daily, you're at the dose shown to support power output and body composition in athletic performance trials — without crossing the 4,000mg threshold where some studies have observed elevated LDL cholesterol. The betaine anhydrous form is the standard used in clinical research.
The tradeoff is pill burden. You need three tablets per serving, and the label suggests up to three tablets twice daily (6,000mg). The product is also highly sensitive to moisture, so you'll need to keep the bottle sealed tightly between uses.
Supports
Score Breakdown
Ingredients (1)
Within effective range
Label Nutrition Facts
Active Ingredients
From the label · % Daily Value
Trimethylglycine (TMG)3000 mg
Other Ingredients
Fillers, coatings, and additives
Magnesium StearateLubricant
Croscarmellose SodiumDisintegrant
Microcrystalline CelluloseBinder
Microcrystalline CelluloseBinder
Stearic AcidLubricant
vegetarian coating
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.