The lead ingredient here is **MSM** (as OptiMSM) at 1,000 mg — right at the minimum clinical dose for connective tissue and sulfur support. You're also getting 50 mg of **Silicon**, well above the studied range, which contributes to collagen cross-linking and hair/nail strength. **Zinc** at 15 mg hits the low end of the clinical range for skin and immune support, and **Copper** at 2 mg is included at an effective dose to keep your zinc-copper ratio balanced.

**Vitamin C** at 120 mg covers your RDA but falls short of the 250+ mg clinical range used in collagen synthesis research. It'll support basic antioxidant needs but isn't enough to meaningfully boost collagen production on its own.

The biggest gap is the amino acid doses. **L-Lysine** at 50 mg is just 5% of the minimum studied dose (1,000 mg), and **L-Proline** at 50 mg is only 10% of its minimum (500 mg). At these amounts, they're unlikely to contribute meaningfully to your skin or hair goals.