If you're looking to support healthy estrogen metabolism, **Diindolylmethane (DIM)** is a compound derived from cruciferous vegetables that may shift the balance toward less potent estrogen metabolites. At 100mg per tablet with a suggested range of 1-4 daily, you can adjust your intake from 100-400mg — the 100-200mg range is where most of the limited human research has been conducted.

The formula includes **Vitamin E** as d-alpha-tocopheryl succinate (33mg, a natural form) and soy **Lecithin** to support absorption, plus black pepper extract at 3mg to enhance bioavailability. What this means for you: these are practical additions since DIM is poorly absorbed on its own.

The honest caveat here: while DIM has a plausible mechanism for estrogen balance, the human clinical evidence is still limited. Most studies are small, and the research on DIM for hormone-related goals like acne, PMS, or body composition is preliminary. The soy-derived lecithin is also worth noting if you have soy sensitivities.

BioStacks
Source Naturals

DIM 100 mg

1 Tablet · 120 servings · $0.17/serving

47 / 100Average

Best for

Score Breakdown

Formulation
47
Safety
100
Final score
47/100

Ingredients (4)

Vitamin E33 mg

66% of effective dose · Premium form

Diindolylmethane100 mg

Within effective range

Black Pepper fruit extract3 mg

60% of effective dose

Lecithin100 mg

8% of effective dose · Budget form

Other Ingredients

Fillers, coatings, and additives

4Safe

Magnesium StearateLubricant

Safe

Silicon DioxideAnti-caking

Safe

Microcrystalline CelluloseBinder

Safe

Stearic AcidLubricant

Safe

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.