If you're looking to support healthy estrogen metabolism, **Diindolylmethane (DIM)** is a compound derived from cruciferous vegetables that may shift the balance toward less potent estrogen metabolites. At 100mg per tablet with a suggested range of 1-4 daily, you can adjust your intake from 100-400mg — the 100-200mg range is where most of the limited human research has been conducted.
The formula includes **Vitamin E** as d-alpha-tocopheryl succinate (33mg, a natural form) and soy **Lecithin** to support absorption, plus black pepper extract at 3mg to enhance bioavailability. What this means for you: these are practical additions since DIM is poorly absorbed on its own.
The honest caveat here: while DIM has a plausible mechanism for estrogen balance, the human clinical evidence is still limited. Most studies are small, and the research on DIM for hormone-related goals like acne, PMS, or body composition is preliminary. The soy-derived lecithin is also worth noting if you have soy sensitivities.
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What it does
A combination of 4 label ingredients.
DIM
Form not confirmedGrade —
Studied for estrogen-metabolism markers, not established cancer prevention; interactions with hormone medicines require caution.
Vitamin E
Mixed formsGrade —
Helps protect cells from oxidative damage and supports normal immune function.
Ingredients (4)
Other ingredients
Magnesium StearateLubricant
A salt of stearic acid used as a lubricant in tablet and capsule production
Silicon DioxideAnti-caking
Fine silica powder used to prevent clumping
Microcrystalline CelluloseBinder
Plant-derived cellulose used as a binder and filler in supplements
Stearic AcidLubricant
Saturated fatty acid used as tablet lubricant
Lab testing
How to take it
With a meal containing fat
On the label
Suggested Use: 1 tablet 1 to 4 times daily with meals.
Price check
$20.99
Near the median of 31 DIM supplements
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from the NIH Office of Dietary Supplements and the National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. studied ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.
Not medical advice. Consult your healthcare professional.