**Saccharomyces boulardii** is among the most evidence-backed probiotics available — over 100 RCTs and multiple meta-analyses show it roughly halves the risk of antibiotic-associated diarrhea. If you're starting an antibiotic course or dealing with gut disruption, this is one of the few probiotic ingredients where the clinical case is genuinely strong.
At one capsule daily (250 mg / 5 billion CFU), you're getting about half the minimum dose used in clinical trials. The label allows up to three capsules, which puts you at 750 mg — solidly within the 500–1,000 mg therapeutic range. Delayed-release capsules help the yeast survive stomach acid, which matters for delivery.
Plan on two to three capsules daily if you want to match the evidence, especially during antibiotic use. The **Manno-oligosaccharides** (100 mg) are a prebiotic addition, but well below studied levels — don't factor them into your decision.
BioStacks
Other Ingredients (5)
Rice ConcentrateAnti-caking
A rice-derived blend used as a natural flow agent and anti-caking aid
Silicon DioxideAnti-caking
Fine silica powder used to prevent clumping
Gellan GumGelling Agent
Microbial polysaccharide produced by Sphingomonas elodea, used as a gelling and stabilizing agent
HypromelloseCapsule
Plant-derived capsule material from cellulose
Microcrystalline CelluloseBinder
Plant-derived cellulose used as a binder and filler in supplements
How to Take It
Take it anytime
Timing doesn't matter for this one — taking it consistently does.
With or without food
On the label
Suggested use: As a dietary supplement, take one veggie DRcaps capsule with water between meals. May take up to three capsules per day.
General guidance based on the ingredients, not a substitute for the label or your doctor.
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.