**Saccharomyces boulardii** is among the most evidence-backed probiotics available — over 100 RCTs and multiple meta-analyses show it roughly halves the risk of antibiotic-associated diarrhea. If you're starting an antibiotic course or dealing with gut disruption, this is one of the few probiotic ingredients where the clinical case is genuinely strong.

At one capsule daily (250 mg / 5 billion CFU), you're getting about half the minimum dose used in clinical trials. The label allows up to three capsules, which puts you at 750 mg — solidly within the 500–1,000 mg therapeutic range. Delayed-release capsules help the yeast survive stomach acid, which matters for delivery.

Plan on two to three capsules daily if you want to match the evidence, especially during antibiotic use. The **Manno-oligosaccharides** (100 mg) are a prebiotic addition, but well below studied levels — don't factor them into your decision.