You're getting 500mg each of **L-Arginine** and **L-Citrulline** per two-capsule serving — but the clinical research on blood flow and exercise performance uses 2,000–6,000mg of arginine and 3,000–6,000mg of citrulline. At these doses, you're at roughly 25% and 17% of the minimum studied amounts, which is well below the range where meaningful nitric oxide support has been demonstrated.

The ingredient pairing itself is sound — your body converts citrulline into arginine in the kidneys, which can sustain nitric oxide levels longer than arginine alone. But that synergy only kicks in at higher doses. At 500mg each, neither ingredient reaches the threshold where clinical benefits for heart health or workout performance have been observed.

To reach even the low end of the studied dose for arginine alone, you'd need to take eight capsules daily — four times the label's recommendation. That makes this a starting point at best, not a clinically effective dose.

BioStacks
Vitamode

L-Arginine Plus L-Citrulline Capsule

2 Capsules · 30 servings

iHerbAmazon

Every active here is dosed below the amount studied to work. See how each one compares in the breakdown below.

Ingredients (2)

L-Arginine

25%

Dose

500 mg

Target

2000–6000 mg

Form

—

L-Citrulline

17%

Dose

500 mg

Target

3000–6000 mg

Form

—

Other Ingredients (1)

HypromelloseCapsule

Plant-derived capsule material from cellulose

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

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