**Magnesium L-threonate** is one of the few magnesium forms shown to cross the blood-brain barrier, which is why it's specifically studied for cognitive and neurological benefits rather than general magnesium repletion. Each three-capsule serving delivers 144mg of elemental magnesium from 1,860mg of the full threonate compound. If your primary goal is brain health or sleep support, this form targets those pathways more directly than common alternatives like citrate or oxide.

Your 144mg per serving falls within the clinical supplemental range of 100-400mg, though it sits on the lower end. That said, threonate is on the UL-safe list, meaning your body tolerates it well at higher intakes without the GI discomfort that can come with other forms. The dosing split — one capsule in the morning, two before bed — aligns with how threonate is typically used in research settings.

The capsule shell is HPMC (plant-based), and there are no additional inactive ingredients beyond that. You're getting a single-ingredient product with nothing else added to the formula. If you're already meeting your baseline magnesium needs through diet or another supplement, this product is designed to layer on the brain-specific benefits that threonate provides.

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YGIA Natural Health

Magnesium L-Threonate 620mg

3 Capsules · 20 servings

iHerbAmazon

Best for

Sleep

Ingredients (1)

Magnesium (as Magnesium L-Threonate)

100%

Dose

144 mg

Target

100–400 mg

Form

Premium

Other Ingredients (1)

HypromelloseCapsule

Plant-derived capsule material from cellulose

How to Take It

Best taken in the evening

Magnesium L-threonate is designed to raise magnesium in the brain — shown in animals. The human cognition trial dosed 1.5–2 g/day, usually split with a dose in the evening.

With or without food
Space it a couple of hours from Iron and Calcium

On the label

Take 3 capsules daily - 1 in the morning and 2 before bedtime, or as recommended by a healthcare practitioner.

General guidance based on the ingredients, not a substitute for the label or your doctor.

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from the NIH Office of Dietary Supplements and the National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. studied ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

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