Why GSH for Liver
For liver support, GSH is a supporting ingredient backed by research. Glutathione is the body's primary intracellular antioxidant, a tripeptide of glutamate, cysteine, and glycine. Oral bioavailability was historically questioned, but the Richie et al. In clinical studies, gsh supports liver detoxification (Phase II conjugation).
Effective dosing
Most evidence supports 250–1000 mg of gsh daily. Landmark 6-month RCT (Richie et al. 2015) used 250 and 1000 mg/day of Setria. 1000 mg raised blood GSH 30-35% and doubled NK cell cytotoxicity. 250 mg showed modest whole-blood increases. Liposomal forms may achieve similar effects at lower doses. Products below this range may not deliver meaningful results.
The evidence behind gsh
Research supporting gsh for liver is rated as moderate. Landmark 6-month trial (54 adults) showed 1000mg/day significantly raised levels and immune function Learn more
