About Cetoleic Acid (Omega-11)
Cetoleic acid (22:1 n-11) is a long-chain monounsaturated omega-11 fatty acid abundant in cold-water pelagic fish oils (herring, capelin, sandeel) but nearly absent from standard EPA/DHA concentrates. Its interest is indirect: preclinical work — chiefly rodent studies from Norwegian marine-oil groups — suggests cetoleic-rich oils raise the body's own EPA and DHA levels more than equivalent EPA/DHA intake alone, positioning it as a possible long-chain-omega-3 booster rather than a direct actor. Human evidence is minimal: no dedicated efficacy RCTs and no established intake target. Claims rest largely on mechanistic and animal data. Not an essential nutrient with its own RDA.
What Cetoleic Acid (Omega-11) supports
- Marine omega-11 fatty acid from pelagic fish oils
- May raise the body's own EPA/DHA levels (preliminary, mostly animal data)
How much Cetoleic Acid (Omega-11) to take
The RDA prevents deficiency. The effective range is what clinical trials used to actually move the outcome.
Effective
100–500
mg
No established cetoleic-acid target. A minor component of pelagic fish oils (herring, capelin, sandeel) — the basis of CETO3-type oils. Products typically supply ~50–200 mg; scored conservatively against published research depth, not a dose-response curve.
Clinical evidence
Limited clinical evidence. Preliminary mechanistic/animal evidence that cetoleic-rich oils boost endogenous EPA/DHA; no dedicated human efficacy RCTs or established dose
NIH Fact Sheet