BioStacks
EPA
Fatty AcidStrong Evidence
Dosing Guide
RDA
None
Effective
500–2000 mg
Upper Limit
None
500mg minimum for general benefit; 1000-2000mg for mood/cardiovascular outcomes.
About EPA
EPA is the primary anti-inflammatory omega-3 fatty acid. EPA-dominant formulas (≥60% EPA) outperform DHA-dominant formulas for mood and depression in multiple meta-analyses. The REDUCE-IT trial used 4g icosapent ethyl (pure EPA) and showed 25% cardiovascular event reduction. rTG form is ~70% better absorbed than ethyl ester. Premium suppliers: AlaskOmega, EPAX.
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