BioStacks
Epitalon
Amino AcidLimited Evidence
Dosing Guide
RDA
None
Effective
1–10 mg
Upper Limit
None
Supplement doses range 1–10 mg/day. One small Russian study (Khavinson, injection). No human RCTs for oral use. Oral bioavailability is uncharacterized.
About Epitalon
A synthetic tetrapeptide (Ala-Glu-Asp-Gly) studied by Russian gerontologist Vladimir Khavinson for telomerase activation and anti-aging. One small, non-blinded Russian study reported increased telomere length in elderly subjects via injection — this study has never been replicated by independent researchers. In-vitro data shows telomerase activation in cell cultures. Zero human RCTs for oral supplementation exist. As a tetrapeptide, oral bioavailability is uncharacterized and likely very low. Popular in longevity/biohacking communities.
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