BioStacks

Epitalon

Amino AcidLimited Evidence
Ep

Dosing Guide

RDA

None

Effective

110 mg

Upper Limit

None

Supplement doses range 1–10 mg/day. One small Russian study (Khavinson, injection). No human RCTs for oral use. Oral bioavailability is uncharacterized.

About Epitalon

A synthetic tetrapeptide (Ala-Glu-Asp-Gly) studied by Russian gerontologist Vladimir Khavinson for telomerase activation and anti-aging. One small, non-blinded Russian study reported increased telomere length in elderly subjects via injection — this study has never been replicated by independent researchers. In-vitro data shows telomerase activation in cell cultures. Zero human RCTs for oral supplementation exist. As a tetrapeptide, oral bioavailability is uncharacterized and likely very low. Popular in longevity/biohacking communities.

NIH Fact Sheet
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