About Copper Peptide
A naturally occurring tripeptide (Gly-His-Lys) that binds copper. Topical studies show wound healing and collagen stimulation in skin — but these are topical application, not oral supplementation. Gene expression studies (Pickart et al.) show broad anti-inflammatory and tissue-remodeling signatures in vitro. Zero human RCTs for oral supplementation exist. Oral bioavailability of the intact peptide is unknown — likely degraded by gastric proteases. Popular in anti-aging biohacking communities.
What Copper Peptide supports
- Topical skin studies exist — zero human RCTs for oral use
- Oral peptide likely degraded by stomach acid; bioavailability unknown
How much Copper Peptide to take
The RDA prevents deficiency. The effective range is what clinical trials used to actually move the outcome.
Effective
100–500
mcg
Oral supplement doses range 100–500 mcg/day. No human RCTs for oral use. Topical studies use 0.01–1% solutions. Oral bioavailability is uncharacterized.
Clinical evidence
Limited clinical evidence. Zero human RCTs for oral use — topical wound healing data exists but does not apply to oral supplements. Peptide likely degraded by gastric proteases.
NIH Fact Sheet