BioStacks

Amino Acid

Glutamate

Evidence

Limited
Evidence: 2 of 5 (Limited)

What the evidence says

Non-essential amino acid and the most abundant excitatory neurotransmitter in the brain. Abundant in dietary protein. As a standalone supplement, evidence for specific health benefits is limited. Plays a role in nitrogen metabolism and serves as a precursor to GABA and glutathione (via glutamate-cysteine ligase).

Essential metabolic amino acid but limited standalone supplementation evidence

Top Glutamate supplements

About Glutamate

Non-essential amino acid and the most abundant excitatory neurotransmitter in the brain. Abundant in dietary protein. As a standalone supplement, evidence for specific health benefits is limited. Plays a role in nitrogen metabolism and serves as a precursor to GABA and glutathione (via glutamate-cysteine ligase). Present in many amino acid blends. Not to be confused with L-glutamine, which is a different amino acid. No established RDA/UL.

What Glutamate supports

  • Precursor to GABA and glutathione
  • Supports nitrogen metabolism and protein synthesis

How much Glutamate to take

The RDA prevents deficiency. The effective range is what clinical trials used to actually move the outcome.

Effective

5002000

mg

Non-essential amino acid; supplemental doses vary widely. Abundant in dietary protein.

Clinical evidence

Limited clinical evidence. Essential metabolic amino acid but limited standalone supplementation evidence

Examine.com