About Vitamin B1
Essential cofactor for glucose metabolism and energy production, particularly in nerve and muscle cells. Benfotiamine is a fat-soluble derivative with up to 5x higher bioavailability than standard thiamine, making it especially beneficial for nerve health. Standard thiamine absorption is limited by intestinal transporters, but benfotiamine bypasses this through lipophilic pathways.
What Vitamin B1 supports
- Converts carbohydrates into energy
- Supports nerve and brain function
How much Vitamin B1 to take
Clinical studies typically use 25–100 mg of Vitamin B1. B-complex supplements typically provide 25–100 mg.
- RDA
- 1.2 mg
- Effective range
- 25–100 mg
Forms of Vitamin B1 compared
- BenfotiaminePremiumFat-soluble thiamine; ~3.6× peak plasma vs. HCl.
- Thiamine HClBudgetBasic form, low bioavailability
- Thiamine mononitrateBudgetBasic form, low bioavailability
Clinical evidence
Strong clinical evidence. Essential for glucose metabolism and nerve function; benfotiamine form has up to 5x higher bioavailability
NIH Fact Sheet