About Zeaxanthin
Zeaxanthin is a xanthophyll carotenoid and an isomer of lutein. It concentrates at the very center of the macula (fovea), while lutein is more peripheral — together they provide complete macular pigment coverage. The AREDS2 trial used the lutein + zeaxanthin combination. Meso-zeaxanthin is a third form found at the peak of the fovea, converted from lutein in the retina. Like lutein, zeaxanthin is not synthesized by the body. Sources include orange/yellow peppers, corn, and egg yolks. No established RDA/UL.
What Zeaxanthin supports
- Concentrates at the fovea — the exact center of sharpest vision
- Works synergistically with lutein for complete macular pigment coverage
- Part of the AREDS2 formula proven to support macular health
- Filters high-energy blue light at the point of greatest visual acuity
How much Zeaxanthin to take
Clinical studies typically use 2–4 mg of Zeaxanthin. AREDS2 study used 2 mg/day; typically paired with lutein.
- Effective range
- 2–4 mg
Clinical evidence
Strong clinical evidence. Confirmed in the AREDS2 trial (5,000+ participants) as part of the macular health formula
NIH Fact Sheet