DIM and hormones
DIM is a supporting nutrient for hormones support. A metabolite of indole-3-carbinol found in cruciferous vegetables. Studied primarily for modulating estrogen metabolism — shifts the 2-OHE1:16α-OHE1 ratio toward the protective 2-hydroxy pathway. RCTs (Del Priore 2010, Dalessandri 2004, Heath 2020) consistently show this biomarker shift at 100–300 mg/day.
Effective dosing
Most evidence supports 100–300 mg of dim daily. 100–300 mg/day of bioavailable (microencapsulated) DIM used in RCTs. Plain crystalline DIM has very poor absorption. Products below this range may not deliver meaningful results.
What the research says
The clinical evidence for dim in hormones is limited. 8–12 small RCTs show consistent estrogen metabolite shifts; no meta-analyses exist; no hard clinical endpoints proven Learn more
