BioStacks

Best EPA for Longevity

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Clinical dose: 500–2000 mg

Why EPA for Longevity

When it comes to longevity, EPA is one of the most supporting nutrients to consider. EPA is the primary anti-inflammatory omega-3 fatty acid. EPA-dominant formulas (≥60% EPA) outperform DHA-dominant formulas for mood and depression in multiple meta-analyses. The REDUCE-IT trial used 4g icosapent ethyl (pure EPA) and showed 25% cardiovascular event reduction.

How much epa do you need

Research points to 500–2000 mg as the effective range for epa. 500mg minimum for general benefit; 1000-2000mg for mood/cardiovascular outcomes. Lower doses may provide some benefit, but most studies showing clear results used this range.

The evidence behind epa

Research supporting epa for longevity is rated as strong. REDUCE-IT (n=8,179) showed 25% CV event reduction with pure EPA. Meta-analyses of 26 RCTs confirm EPA-dominant formulas superior for depression. Learn more