BioStacksHow Leucine supports muscle
Leucine is a important nutrient for muscle support. Essential branched-chain amino acid (BCAA). Primary activator of mTOR signaling and muscle protein synthesis. Most studied of the three BCAAs with well-established role in MPS. In clinical studies, leucine triggers muscle protein synthesis via mTOR activation.
How much leucine do you need
Research points to 2000–5000 mg as the effective range for leucine. 2–3 g is the 'leucine threshold' for triggering muscle protein synthesis; 5 g common in BCAA blends. Lower doses may provide some benefit, but most studies showing clear results used this range.
Clinical research
Leucine has strong clinical evidence for muscle benefits. Primary trigger for mTOR-dependent muscle protein synthesis; 2-3g is the threshold for maximal activation Learn more
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