BioStacks

Supplement

Beta-Cryptoxanthin

Evidence

Limited
Evidence: 2 of 5 (Limited)

What the evidence says

A provitamin-A xanthophyll carotenoid concentrated in citrus and orange peppers. As with alpha-carotene, the human data are epidemiological: higher serum beta-cryptoxanthin is associated with lower lung-cancer death (NHANES III HR ~0.21) and, in some cohorts, better bone and joint outcomes.

Provitamin-A carotenoid; epidemiological associations only, no supplementation RCTs.

Top Beta-Cryptoxanthin supplements

About Beta-Cryptoxanthin

A provitamin-A xanthophyll carotenoid concentrated in citrus and orange peppers. As with alpha-carotene, the human data are epidemiological: higher serum beta-cryptoxanthin is associated with lower lung-cancer death (NHANES III HR ~0.21) and, in some cohorts, better bone and joint outcomes. These are dietary-pattern associations; there are no RCTs of isolated beta-cryptoxanthin supplementation showing clinical benefit. Grade low.

What Beta-Cryptoxanthin supports

  • Higher intake/levels associated with better lung and bone health in observational studies
  • One of the few carotenoids that converts to vitamin A

How much Beta-Cryptoxanthin to take

The RDA prevents deficiency. The effective range is what clinical trials used to actually move the outcome.

Effective

00

mcg

No established therapeutic dose. A minor provitamin-A xanthophyll, usually a trace natural companion in mixed-carotenoid, citrus or paprika blends. Nominal placeholder range.

Clinical evidence

Limited clinical evidence. Provitamin-A carotenoid; epidemiological associations only, no supplementation RCTs.

NIH Fact Sheet