BioStacks

Herb

Chicory

Evidence

Limited
Evidence: 2 of 5 (Limited)

What the evidence says

Chicory (Cichorium intybus) has limited but positive clinical evidence for liver support. A 2023 meta-analysis of 5 RCTs (197 NAFLD patients) found significant reductions in liver enzymes AST (-7 U/L) and ALT (-17.5 U/L). A separate RCT in burn patients showed prevention of liver enzyme elevation.

Meta-analysis of 5 small trials (197 patients) showed reduced liver enzymes in fatty liver disease

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About Chicory

Chicory (Cichorium intybus) has limited but positive clinical evidence for liver support. A 2023 meta-analysis of 5 RCTs (197 NAFLD patients) found significant reductions in liver enzymes AST (-7 U/L) and ALT (-17.5 U/L). A separate RCT in burn patients showed prevention of liver enzyme elevation. Also a natural source of inulin (prebiotic fiber), though the liver benefits appear independent of inulin content. Small sample sizes across studies.

What Chicory supports

  • May reduce liver enzymes in NAFLD (meta-analysis of 5 RCTs)
  • Natural source of prebiotic inulin fiber

How much Chicory to take

The RDA prevents deficiency. The effective range is what clinical trials used to actually move the outcome.

Effective

10003000

mg

Root extract doses from RCTs. Also used as chicory seed syrup in some studies.

Clinical evidence

Limited clinical evidence. Meta-analysis of 5 small trials (197 patients) showed reduced liver enzymes in fatty liver disease

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