About Whole coffee fruit (NeuroFactor)
Whole coffee fruit (cherry) extract standardized for chlorogenic acids and other polyphenols; marketed (e.g. NeuroFactor) with claims of raising serum BDNF. Evidence is limited to small, mostly industry-funded studies measuring blood BDNF as a surrogate; no robust cognitive-outcome RCTs. Contains little caffeine.
What Whole coffee fruit (NeuroFactor) supports
- Polyphenol-rich; small studies report raised blood BDNF, without hard cognitive outcomes
How much Whole coffee fruit (NeuroFactor) to take
The RDA prevents deficiency. The effective range is what clinical trials used to actually move the outcome.
Effective
100–200
mg
Small BDNF studies of the branded whole-coffee-fruit extract used ~100 mg. Nominal range.
Clinical evidence
Limited clinical evidence. Small, mostly industry-funded surrogate-marker studies.