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Lithium

Mineral
Li
Moderate Evidence

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About Lithium

Lithium is a trace mineral found naturally in water and food. Low-dose lithium orotate is used in supplements for mood and cognitive support. Not to be confused with prescription lithium carbonate used for bipolar disorder at much higher doses. Generally well tolerated at nutritional doses. No established RDA/UL for nutritional lithium.

What Lithium supports

  • May support mood balance and emotional well-being at low doses
  • May support neuroprotection and brain health
  • Emerging research on longevity and cellular health at trace doses

How much Lithium to take

Clinical studies typically use 500–5000 mcg of Lithium. Low-dose lithium orotate supplements typically provide 500–5000 mcg (0.5–5 mg) elemental lithium. This is far below prescription lithium doses (typically 600–1800 mg lithium carbonate).

Effective range
500–5000 mcg

Clinical evidence

Moderate clinical evidence. Prescription form is well-studied for bipolar; low-dose supplement evidence is limited to observational data

NIH Fact Sheet
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