About NMN
NMN is a direct precursor to NAD+ (nicotinamide adenine dinucleotide), a coenzyme critical for energy metabolism, DNA repair, and sirtuin activation. Not to be confused with niacin (vitamin B3) or nicotinamide riboside (NR), which are separate NAD+ precursors. Generally well tolerated in studies to date. No established RDA/UL.
What NMN supports
- Supports NAD+ levels, critical for cellular energy and DNA repair
- May support mitochondrial function and energy metabolism
- Emerging research on neuroprotection and cognitive support
- Activates sirtuins, linked to healthy aging pathways
How much NMN to take
Clinical studies typically use 250–1000 mg of NMN. Most human studies use 250–1000 mg/day. 500 mg is the most common supplemental dose. Higher doses (up to 1200 mg) have been used in clinical trials.
- Effective range
- 250–1000 mg
Clinical evidence
Moderate clinical evidence. Growing body of human trials on NAD+ levels, but long-term health outcomes are still emerging
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