About Polyphenols
Class marker, not a discrete compound. 'Polyphenols' spans flavonoids, phenolic acids, stilbenes, lignans and more, with wildly different potencies and evidence bases. Observational diet studies link higher polyphenol intake to cardiometabolic benefit, but this cannot be attributed to a generic 'polyphenol' dose in a supplement. Where a specific source is named (green tea, grape seed, olive), score that named entry instead. Present here mainly to resolve the label term and kill the 'not in our database' flag.
What Polyphenols supports
- Dietary polyphenol intake is associated with cardiometabolic health in population studies (association, not proof of a supplement effect)
- Act as antioxidants in lab and mechanistic studies
How much Polyphenols to take
The RDA prevents deficiency. The effective range is what clinical trials used to actually move the outcome.
Effective
100–1000
mg
No established therapeutic dose; 'polyphenols' is a broad chemical class (thousands of compounds), not a single active. Nominal range for a blend marker. On labels this usually appears as a standardization percentage (e.g. '30% Polyphenols') of a plant extract rather than a dosed active.
Clinical evidence
Limited clinical evidence. Broad chemical class; diet-level associations only, no clinical dose for a generic 'polyphenol' supplement.